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Using this medication may lead to mild side effects such as itching, redness, burning, and stinging at the application site. These effects are usually not serious, but if the redness persists beyond four days, it's important to discontinue use and consult a healthcare professional. Other common effects include nausea, dizziness, flushing, heartburn, or headache. Additionally, nicotine withdrawal symptoms, such as anxiety, depression, or trouble sleeping, may occur when ceasing smoking.

While serious side effects are uncommon, they are more likely if you continue smoking while using the medication. Serious symptoms to watch for include mood changes like irritability, sleep disturbances, vivid dreams, numbness or tingling in the extremities, or swelling in the hands, ankles, or feet. If you experience these, it's crucial to stop using the product and seek medical advice promptly.

In rare cases, very serious side effects can occur, such as chest pain, confusion, severe headache, irregular heartbeat, difficulty speaking, or weakness on one side of the body. Immediate medical attention is necessary if these symptoms arise. Additionally, although rare, a severe allergic reaction may occur, characterized by rash, swelling, severe dizziness, or difficulty breathing. If any of these symptoms present, emergency medical help is needed immediately.

While this is not an exhaustive list of side effects, any other unusual effects should also be reported to a healthcare provider.