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Etanercept is a medication that can affect your immune system, which may increase your risk of developing serious infections or other health issues. It is important to understand the potential risks and precautions associated with its use. Always consult your healthcare provider with any questions or concerns you may have. Below are key safety considerations:

• Infection Risk: Etanercept may lower your ability to fight infections, making you more susceptible to serious infections, including fungal and bacterial infections like tuberculosis. Inform your doctor of your medical history, particularly any past or current infections, and if you have lived or traveled in areas where specific fungal infections are prevalent. Testing for tuberculosis should be done before and during treatment. Seek medical attention if you experience signs of infection, such as persistent sore throat, cough, fever, night sweats, or unusual vaginal discharge.

• Cancer Risk: There is a potential risk of developing certain types of cancer, such as lymphoma or skin cancer, especially in children, teens, and young adults. Discuss the risks and benefits of treatment with your healthcare provider. Report any symptoms like unexplained lumps, persistent fever, or weight loss to your doctor immediately.

• Nervous System Effects: Although rare, etanercept can lead to new nervous system disorders like multiple sclerosis or Guillain-Barré syndrome. Inform your healthcare provider if you have existing nerve issues, and be vigilant for symptoms such as numbness, tingling, or vision problems, as these conditions can become serious.

• Heart Failure: Etanercept may cause new or worsening heart failure. Notify your provider if you have heart failure so they can evaluate if this medication is suitable for you.

• Blood and Infection Concerns: In rare cases, etanercept can reduce blood cell counts, affecting your ability to fight infections and increasing bleeding risk. Contact your doctor if you notice persistent fever, easy bruising, or unusual bleeding.

• Contraindications: Do not use etanercept if you have active infections or a history of serious infections like sepsis. Discuss any other medications you are taking and your full medical history with your healthcare provider prior to starting etanercept.

In the event of a suspected overdose or severe reaction, seek emergency medical assistance immediately. Regular monitoring by your healthcare provider is crucial to manage any potential side effects or complications while on etanercept.

When using this medication, some common side effects may occur, including redness, itching, pain, or swelling at the injection site, which typically resolves within a few days. Headaches and mild infections such as the common cold or flu may also occur. It's important to note that these side effects often diminish after the first month. Diarrhea is another possible mild side effect, though it appears less frequently.

There are other side effects that you might experience, such as a rash or hives, itching, and fever. Although these are generally not severe, it's advisable to consult your healthcare provider if they persist or worsen.

On a more serious note, there are rare but significant side effects that necessitate immediate medical attention. These include signs of liver disease, such as persistent nausea or vomiting, dark urine, stomach pain, or yellowing of the eyes or skin. Additionally, symptoms like a butterfly rash on the face, severe headache, unusual bruising, mood changes, seizures, muscle weakness, or vision changes should be addressed promptly. Serious infections marked by high fever, persistent cough, or difficulty breathing, as well as severe allergic reactions, require urgent medical care. If you experience any severe symptoms, it's crucial to seek medical help immediately.