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The following safety information outlines crucial warnings related to the use of this medication. It is essential to understand these risks and discuss any concerns with your healthcare provider:

• Alterations in Stress Hormone Levels: Budesonide, a corticosteroid, mimics the stress hormones produced naturally by the body. Prolonged use or higher doses can lead to decreased production of these hormones by the body, causing dependency on the medication. This is especially a concern for individuals taking high doses, using the medication long-term, children, and those with liver issues.

• Increased Infection Risk: Budesonide can compromise your immune system, heightening the likelihood of infections. If you suspect an infection, such as fungal, bacterial, or viral, or if you've recently traveled to areas with high infection risks, consult your healthcare provider immediately. Symptoms to watch for include fever, fatigue, chills, cough, or breathing difficulties. Seek medical attention promptly if these occur.

• Exacerbation of Pre-existing Conditions: Budesonide can aggravate certain medical conditions, including hypertension, diabetes, osteoporosis, stomach ulcers, and glaucoma. It is vital to inform your gastroenterologist about your complete medical history to ensure appropriate monitoring while using this medication. They will advise you on the symptoms to monitor and when to seek medical care. This risk is particularly pertinent for individuals with a history of high blood pressure, high blood sugar, bone weakening, stomach ulcers, glaucoma, cataracts, or a family history of diabetes or glaucoma.

Please note, there are no specific contraindications listed for this medication. Always follow the guidance of your healthcare provider when using this treatment.

Budesonide is a medication that tends to have fewer side effects compared to other corticosteroids, primarily because it acts in the gut with minimal absorption into the bloodstream. Common side effects include headache, nausea, abdominal pain, upset stomach, and dizziness; these are generally mild and should not cause concern unless they persist or worsen. Other common symptoms might include respiratory infections, back pain, gas, vomiting, fatigue, pain, diarrhea, sinus inflammation, and viral infections. If any of these persist, it is advisable to consult a healthcare provider.

While most patients do not experience serious side effects, budesonide can lower your immune system's ability to fight infections, potentially leading to more severe infections. If you notice signs of infection such as persistent sore throat, fever, or chills, seek medical advice promptly. There is also a risk of oral thrush or yeast infections, so be aware of symptoms like white patches in the mouth or changes in vaginal discharge.

Serious side effects, though rare, require immediate medical attention. These include easy bruising, swelling of the face (moon face), unusual weight gain, mental changes like mood swings or depression, muscle or bone pain, thinning skin, slow wound healing, increased thirst or urination, vision changes, and symptoms indicative of stomach or intestinal bleeding. An allergic reaction to budesonide is uncommon but can be severe, marked by rash, itching, swelling, severe dizziness, or difficulty breathing. If you experience these symptoms, seek medical intervention immediately. Always report any new or unusual side effects to your healthcare provider for further guidance.

Budesonide can interact with several medications, so it is essential to inform your doctor and pharmacist about all the medications and supplements you are taking, whether they are prescription, over-the-counter, vitamins, or herbal supplements. Some specific drugs that may interact with Budesonide include:

1. Desmopressin: Using Budesonide with desmopressin is generally not recommended. Your doctor might opt for a different treatment or adjust your medication regimen.

2. NSAIDs and Blood Thinners: Medications like clopidogrel, dabigatran, warfarin, aspirin, celecoxib, and ibuprofen, which can cause bleeding or bruising, should be used with caution. If you're advised to take low-dose aspirin for heart disease prevention, continue unless your doctor advises otherwise.

3. Erythromycin and Ketoconazole: These may increase the risk of certain side effects when used with Budesonide. Your doctor might adjust dosages or usage schedules.

4. Various Other Medications: A wide range of other drugs, including many anti-inflammatory and antibiotic medications, might require dosage adjustments or additional monitoring if used with Budesonide.

Additionally, Budesonide may interfere with certain lab tests, potentially leading to inaccurate results. Ensure all healthcare personnel are aware of your Budesonide use to prevent this issue. Always seek guidance from your healthcare provider for personalized advice and adjustments to your treatment plan.