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The information below outlines important safety warnings and precautions for the use of Epiduo (adapalene/benzoyl peroxide). It is essential to understand these risks and discuss any concerns with your healthcare provider.

• Increased Sun Sensitivity: Epiduo may heighten your skin's sensitivity to sunlight, increasing the risk of severe sunburn. To reduce this risk, limit sun exposure, and avoid sunlamps and tanning beds. When outdoors, protect your skin by wearing sunscreen and appropriate clothing, such as hats and long sleeves.

• Skin Reactions: Use of Epiduo can lead to skin irritation, including dryness, redness, and a stinging or burning sensation, particularly during the initial month of treatment. To alleviate these effects, apply a gentle, non-medicated moisturizer. Avoid applying Epiduo to areas with cuts, scrapes, wounds, or bruises, as this can exacerbate irritation. Additionally, refrain from hair waxing on treated skin areas to prevent further damage. If your symptoms persist or worsen, your healthcare provider may adjust your treatment frequency or discontinue use.

• Contraindications: Do not use Epiduo if you have a known allergy to adapalene or benzoyl peroxide. Doing so could result in serious health risks. Always consult your healthcare professional if you have concerns about allergic reactions or other contraindications.

When using this medication, you may experience some common side effects, primarily during the first few weeks. These include skin redness, dryness, peeling, mild burning, and a potential worsening of acne. These effects often subside with continued use. Should they persist or worsen, it's advisable to consult your healthcare provider, who may suggest adjustments like using a moisturizer or altering the frequency of application.

Among the common side effects, dry skin and rashes occur in a small percentage of users. These are generally mild, but if they continue, reach out to your healthcare provider for guidance. Some individuals report skin irritation as well, which should also be monitored.

While rare, more serious side effects can occur and require immediate medical attention. These include severe skin burning, scaling, and pronounced redness. Additionally, a very serious allergic reaction is uncommon but can be identified by symptoms like rash, itching or swelling, severe dizziness, and difficulty breathing. If you experience any of these severe side effects, seek medical help promptly. Remember, these reactions are not exhaustive, so if you notice any other concerning effects, consult your healthcare provider.