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The following safety information outlines potential risks and precautions associated with the use of Forteo (teriparatide). It is crucial to review these warnings and consult your healthcare provider if you have any questions or concerns.

• Bone Cancer (Osteosarcoma): There have been cases where individuals using Forteo (teriparatide) developed osteosarcoma, a rare type of bone cancer. Due to the rarity of this condition, the exact risk associated with the medication is uncertain. Forteo (teriparatide) is not recommended for individuals with certain bone conditions or those with a heightened risk of bone cancer. Healthcare providers generally advise discontinuing the use of Forteo (teriparatide) after two years, as long-term effects beyond this period are not well-documented. At-risk populations include those with rickets, Paget's disease, growing long bones, a history of bone cancer or metastasis to the bones, previous radiation therapy, or genetic predispositions to bone cancer.

• High Calcium Levels: Forteo (teriparatide) may elevate calcium levels in the blood. If you have any pre-existing condition that predisposes you to high calcium levels, you should avoid using this medication. Symptoms of elevated calcium levels include fatigue, irregular heartbeat, muscle weakness, constipation, or loss of appetite. Inform your healthcare provider of any such symptoms or conditions before starting Forteo (teriparatide).

• Kidney Stones: There is a potential for kidney stones to develop in people using Forteo (teriparatide), particularly if calcium levels in the blood and urine are elevated. If you have a history of kidney stones or high urinary calcium levels, consult your healthcare provider before beginning treatment. Be alert for severe lower back or side pain, nausea, vomiting, or changes in urine appearance or odor, as these could indicate kidney stones.

• Low Blood Pressure: Forteo (teriparatide) may cause a temporary drop in blood pressure, particularly when standing after sitting or lying down, leading to dizziness or lightheadedness. This effect is most common during initial doses and typically occurs within four hours of injection. To mitigate this, remain seated or reclined during administration. If dizziness persists or worsens, contact your healthcare provider.

• Interactions with Digoxin (Lanoxin): Using Forteo (teriparatide) alongside digoxin (Lanoxin) may increase the risk of digoxin toxicity, as both can elevate calcium levels. Symptoms of digoxin toxicity include gastrointestinal upset, vision changes, and irregular heart rhythms. If you are on both medications, monitor for unusual heartbeats and consult your healthcare provider if such symptoms arise.

Currently, there are no specified contraindications for Forteo (teriparatide). Always discuss your full medical history with your healthcare provider before starting this medication to ensure it is safe for your specific health needs.

When using this medication, some individuals may experience common side effects such as body pain, joint pain, runny nose, nausea, body weakness, headache, dizziness, and high blood pressure. These symptoms are generally mild and should subside as your body adjusts. However, if they persist or worsen, it's advisable to consult your healthcare provider for guidance. Additionally, you might notice other side effects like cough, sore throat, constipation, diarrhea, vomiting, indigestion, or vertigo. These are also generally manageable, but do seek advice if they become troublesome.

Some side effects, though rare, are more serious and require prompt medical attention. These include symptoms of high calcium levels in the blood, such as unusual tiredness, an abnormal or irregular heartbeat, or muscle weakness. Be alert for new or worsening open wounds or ulcers on your skin. There is a potential risk of bone cancer associated with this medication, as observed in animal studies, though it is uncertain if this applies to humans. Report any bone pain or unusual lumps to your doctor immediately.

While a severe allergic reaction is uncommon, be vigilant for signs such as rash, itching or swelling, especially of the face, tongue, or throat, severe dizziness, or trouble breathing. If these occur, seek medical help without delay. Remember, many individuals use this medication without experiencing serious side effects. If you notice any other unexpected effects, consulting your healthcare provider is always a good practice.