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The following safety information highlights essential precautions and risks associated with the use of NovoLog (insulin aspart). Please read carefully and consult your healthcare professional if you have any questions or concerns.

• Infection Risk from Shared Injection Supplies: Do not share NovoLog pens, syringes, needles, or cartridges with others. Sharing these items can lead to the transmission of serious infections.

• Hypoglycemia (Low Blood Sugar): Using NovoLog alone or in combination with other diabetes medications can result in dangerously low blood sugar levels, which may be life-threatening. Ensure you are using the correct medication as prescribed, especially when using multiple insulin types. Situations that may increase this risk include changes in diet or exercise, switching insulin types, alcohol consumption, use of additional diabetes medications, or existing liver or kidney issues.

• Hypokalemia (Low Blood Potassium Levels): NovoLog may cause a decrease in blood potassium levels, which can be hazardous. This risk is heightened if you are taking other medications that lower potassium, such as certain diuretics. Regular monitoring of potassium levels by your healthcare provider is advised. Report symptoms like weakness, muscle cramps, nausea, vomiting, or irregular heartbeats to your provider.

• Fluid Retention and Heart Failure Risk: Using NovoLog with glitazones (thiazolidinediones), such as pioglitazone, can lead to fluid retention, potentially exacerbating or causing heart failure. Inform your provider if you experience sudden weight gain or symptoms of heart failure, like difficulty breathing, fatigue, or headaches. Medication adjustments may be necessary.

• High Blood Sugar or Ketone Buildup for Insulin Pump Users: If you use an insulin pump, ensure it functions correctly to avoid extremely high blood sugar or ketoacidosis, a severe diabetes complication. Contact your healthcare provider immediately if your pump malfunctions, and consider alternative NovoLog administration methods. Report symptoms such as fatigue, fruity-smelling breath, or vomiting to your provider promptly.

• Contraindications: Do not use NovoLog if you are experiencing low blood sugar (hypoglycemia), as it can cause severe health issues. Always consult with your healthcare provider before starting this medication if you have any contraindications.

When using this medication, some common side effects you might encounter include mild injection site reactions, such as pain, redness, or irritation. Weight gain may also occur. These effects are usually not serious, but if they persist or worsen, it's important to consult your healthcare provider.

Low blood sugar, or hypoglycemia, can be a concern with this medication and may present symptoms like sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling in the hands and feet. Ensure you have glucose tablets or a quick sugar source to manage this. Conversely, high blood sugar symptoms, such as increased thirst and urination, should be reported to your healthcare provider as they may require adjustments in your treatment plan.

Some individuals report other side effects, including headaches, nausea, diarrhea, muscle sluggishness, and skin problems. While these are generally mild, notify your healthcare provider if they become bothersome. More serious side effects, though rare, include severe allergic reactions, characterized by rash, swelling, severe dizziness, or difficulty breathing. Seek immediate medical attention if these occur.

Other notable side effects can include accidental injury, fungal nail infection, impairment of senses, urinary tract infections, sinus infections, chest pain, and stomach pain. Although these are less common, it's crucial to be aware and discuss any concerns with your healthcare provider.