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When using Rezurock (belumosudil), it is crucial to be aware of certain safety considerations to protect yourself and those around you. Below are essential warnings and precautions regarding its use:

• Risk to Unborn Babies: Animal studies indicate that Rezurock (belumosudil) may cause serious harm, including death or severe birth defects, if used during pregnancy.
  • Precautionary Measures: Women who can become pregnant and men with partners who can become pregnant should employ effective contraception throughout the course of treatment and for at least one week following the final dose.
  • Consultation Advice: If you are pregnant or planning to conceive, it is vital to discuss the use of Rezurock (belumosudil) with your healthcare provider prior to starting the medication.

Please note there are currently no known contraindications for this medication. Always consult with your healthcare provider for personalized advice and if you have any concerns about using Rezurock (belumosudil).

When taking this medication, you might experience some common side effects. These include nausea, diarrhea, abdominal pain, headache, and joint or muscle pain. It's also possible to notice swelling in your ankles, feet, or hands, as well as a cough, tiredness, or shortness of breath. These effects are generally mild, but if they persist or worsen, consulting your healthcare provider is advisable for reassurance and guidance.

Some individuals may experience an increase in blood pressure, so it's important to monitor it regularly. If it becomes elevated, your doctor may recommend adjustments to manage it effectively. Less common side effects like fever, poor appetite, muscle spasms, and nasal congestion have also been reported. Although these are usually manageable, it's best to discuss them with your healthcare provider if they become bothersome.

In rare cases, severe side effects may occur, such as signs of infection like a persistent sore throat, fever, or chills, as well as easy bruising or bleeding. A very serious allergic reaction, characterized by rash, severe itching, swelling, severe dizziness, or trouble breathing, requires immediate medical attention. Pregnant individuals should be aware of the severe risk this medication poses to babies, including potential physical defects or more serious outcomes. If you experience any unusual effects not listed here, reach out to your doctor or pharmacist for advice.