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It is crucial to be aware of the safety information and warnings associated with the use of this medication. Below are key points to consider, and it is advised to consult your healthcare provider if you have any questions or concerns.

• Symptom Masking: Repeated heartburn could indicate stomach cancer. If your heartburn persists or worsens after taking dexlansoprazole (Dexilant), or if you experience poor appetite, unexplained weight loss, or weakness, consult your healthcare provider.

• Kidney Issues: Sudden kidney problems can occur with PPIs like dexlansoprazole (Dexilant) at any treatment stage. Symptoms such as changes in urination, nausea, weakness, fever, rash, or joint pain should be reported to your doctor.

• Infectious Diarrhea: PPIs may increase the risk of Clostridioides difficile infection, causing severe diarrhea, especially in older adults, those with recent hospital stays, or weakened immune systems. Use dexlansoprazole as prescribed and contact your doctor if you experience severe diarrhea, fever, abdominal pain, loss of appetite, or nausea.

• Bone Fractures: Long-term or high-dose use of dexlansoprazole (Dexilant) can increase the risk of fractures. Discuss with your healthcare provider if you have a history of fractures or osteoporosis.

• Skin Reactions: Serious skin reactions, like Stevens-Johnson syndrome or toxic epidermal necrolysis, are rare but possible. Seek immediate medical attention if you experience fever, rash, peeling skin, blisters, or facial swelling.

• Lupus: Dexlansoprazole (Dexilant) may cause new or worsening lupus symptoms, such as joint pain or rash. If symptoms occur, discontinue use and contact your healthcare provider.

• Vitamin B12 and Magnesium Deficiency: Prolonged use can lead to deficiencies in vitamin B12 and magnesium. If you've been on this medication for over three years or notice symptoms like dizziness, muscle weakness, pale skin, fatigue, or tingling, consult your doctor.

• Drug Interactions: Certain drugs can alter dexlansoprazole (Dexilant) levels or efficacy. Avoid using St. John’s Wort and rifampin while on this medication.

• Contraindications: Avoid using this medication with rilpivirine-containing drugs like Edurant and Cabenuva due to potential serious health risks. Always consult your healthcare provider if you are using or considering these medications.

When taking this medication, some common side effects may occur. These include diarrhea affecting about 5% of users, belly pain in 4%, and nausea in 3%. While these side effects are generally mild, it's wise to consult a healthcare professional if they persist or become bothersome.

Other side effects that some individuals may experience include headaches, belly pain, diarrhea, symptoms of the common cold, and pain in the mouth and throat. These effects are reported in more than 5% of users. Though they are usually not severe, notifying a healthcare provider can be helpful if they cause discomfort.

In rare instances, more serious side effects can arise, requiring immediate medical attention. These include upper respiratory infections, vomiting, and passing gas. If any of these occur, it is crucial to seek urgent medical care to ensure your well-being.